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Basal-like carcinoma : ウィキペディア英語版
Basal-like carcinoma

The basal-like carcinoma is a recently proposed subtype of breast cancer defined by its gene expression and protein expression profile.〔Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma, Modern Pathology 19:264-271 (2006), via (www.nature.com )〕 In the current WHO breast tumor classification, these tumors are classified as ductal carcinoma. They are high grade, "triple-negative" tumors, i.e. they express no estrogen receptor, progesterone receptor or Her2/neu proteins.
Basal-like carcinomas tend to be more aggressive, with a poor prognosis. In the U.S., they are more frequent among black women, which may explain the higher breast cancer mortality rate in this group.
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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